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KMID : 0378019720150020049
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New Medical Journal
1972 Volume.15 No. 2 p.49 ~ p.52
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Effect of Co Intoxication on the Oxygen Consumption Rates of Liver, Kidney and Red Blood Cell in Rabbits
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申基棟/Shin, Kee Dong
李圭源/吳相由/李東一/申鉉鑽/Rhee, Kyoo Won/Oh, Sang Yu/Lee, Dong Il/Shin, Hyun chan
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Abstract
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In an attempt to observe a possible effect of CO intoxication on the oxygen consumption rates (Q02) of liver, kidney and red blood cell, the rabbit was exposed to either 0.2% CO gas for six hours or 0.1
CO gas for two hours daily for five days. The Q02 of the liver, kidney and red blood cell was measured by the Warburg´s standard manometric method, and a comparison was made with the control.
The results obtained are summarized as follows:
1. The Q02 of the liver, kidney and red blood cell in the normal rabbit was 1.82±0.3111 02/hr. /mg. D. W., 4.67±0.57 pl 02/hr. /mg. D. W. and 4.40 ? 10´9 pl 02/hr. /RBC, respectively.
2. In the group where the rabbit was exposed to 0.1% CO gas for two hours daily for five days, the QO2 of the liver, kidney and red blood cell was 1.41±0.24, 4.62±0.54 and 4.12.10-9, respectively.
3. The QOz of the liver, kidney and red blood cell in the 0.2% CO exposed group was 1. 75±0. 24, 4.70±0.72 and 4.10. 10´9; respectively.
4. From the above, it may be concluded that CO gas as used in this study do not produce a significant change in Q02 of the some organs from the control.
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